MRSA Discussion Forum USA and Canada

       Home    1

number of replies (14) - Page 1 of 1
Need Help with MRSA blood tests
Started by ladyk
Posted: January 2, 2007 at 17:06
Any who have had blood tests which reveled MRSA could you please check to see and let me know what the specific test was called which showed MRSA in your blood.

Has anyone had serious, ongoing, MRSA outbreaks when no MRSA was found on their blood tests?

8793
Re: Need Help with MRSA blood tests
Reply #1 by sandi
Posted: January 8, 2007 at 05:08
I have never had a blood test that showed MRSA. I have had fluid from around my ankle tested to show MRSA. I had one Boil tested to show MRSA. What they do with my blood test is look a the sed rate. This is a kind of indicator or what the MRSA is doing in your blood. I hope this helps. Sandi
8872
Re: Need Help with MRSA blood tests
Reply #2 by ladyk
Posted: January 9, 2007 at 15:24
Yes it really does help, thank you sandi. Needed a tip of what to look for (sed rate) so I can double check. Seems some time back I had read a specific test had to be done in order to find MRSA in the blood, even though other indicators are present leaning toward infection.
8879
Re: Need Help with MRSA blood tests
Reply #3 by Callie
Posted: January 9, 2007 at 17:41
The sedimentation rate (or ESR - erythrocyte sedimentaion rate) is a very vague test and is only indicative of general infection not specifically MRSA.

To confirm MRSA bacteria actually in the blood you would need to do blood cultures - these are not specific for MRSA but would detect it or any other bacteria present - blood should not grown any bacteria.
8880
Re: Need Help with MRSA blood tests
Reply #4 by ladyk
Posted: January 11, 2007 at 18:20
Thank you Callie. I have just recently had blood cultures done along with multiple other blood panel tests. Although I have not personally seen these test results on paper yet, the physician who did these tests stated over the phone to me that all tests returned negative. Previous regular blood tests showed elevation in white cells, an indicator of infection. Iím assuming such a vague blood test which only shows elevation in white cells is a non specific indicator of infection which could be anywhere in the body.

It seems quite extraordinary that one who has MRSA detected via needle stick culture of skin lesions, (as I have been, with multiple outbreaks over the past nine months, and being as deathly ill as I have been over these past months) yet at this late date MRSA is not detected in my blood. Since during the height of outbreaks Infectious Disease specialists would not do blood culture tests, but prescribed antibiotics such as 30 days of Sulfamethoxazole TMP DS (Bactrim), followed by Flagyl, Vancomycin, and Xifaxan (Rifaximin), among others... I wonder if it is possible these meds killed off blood infection? Yet Iíve since had I think 2 or 3 outbreaks of skin lesions. Really trying to figure all this out.

To back track a bit, Staphylococcus and Pseudomonas were detected in a surgical wound. Soon after, the first outbreak occurred. A needlestick culture was done directly into two of the lesions which grew MRSA. Months later I ended up with C-diff after ingesting a dozen different antibiotics prescribed by doctors trying to kill the Pseudomonas and MRSA. I also am at a bit of a disadvantage due to borderline diabetes which is in great control with A1C being 5.9. Some doctors initially believed my diabetes was the cause of the frequent outbreaks, being immune compromised, which since has been retracted due to A1C showing better than normal standards, although control is greatly due to oral medications.

I donít get it. How can a virulent bacterial infection of the skin such as MRSA is, cause such havoc ďwithinĒ oneís system creating such malaise, yet be so elusive as to not show in the blood after months and months of infections? I wonder if this means outside of the known MRSA strains (HA-MRSA, CA-MRSA) there are strains which do not cross over from skin to blood/organs/etc?



8888
Re: Need Help with MRSA blood tests
Reply #5 by lauren
Posted: January 11, 2007 at 23:58
it takes all of your energy away.

ur legs and feet can go numb after walking just a short distance.

be SURE to keep hydrated, as you might notice ur skin sagging.

eat healthy foods, especially fresh fruits and vegetables, decontaminate refrigerator by first setting the cold level to highest for several days. use bleach or alcohol to disinfect, NEVER MIX bleach with any other chemicals.




8892
Re: Need Help with MRSA blood tests
Reply #6 by Callie
Posted: January 12, 2007 at 18:12
To have MRSA actually in your blood in any other than a transient nature would make you gravely ill. Although it probably doesnt seem like it to you but skin lesions/boils/wound infections are relatively sepearate and protected from the blood system - your body will also do things to fight the infected area and limit any chances of infection passing into the blood. I do not know the exact nature of your infections ladyk - are they boils?

Most people will have transient bacteria in the blood and these come from silly things like brushing your teeth (where mouth bacteria enter the blood stream via cuts/bleeding gums) but the body easily deals with this, stops the bacteria multiplying and destroys them.

In septicaemia, a true infection of the blood - the amount of bacteria would be overwhelming for the body to cope with.

If someone has an infection in a wound/boil it does not always follow that this will lead to septicaemia however it is a risk.

"How can a virulent bacterial infection of the skin such as MRSA is, cause such havoc ďwithinĒ oneís system creating such malaise, yet be so elusive as to not show in the blood after months and months of infections? I wonder if this means outside of the known MRSA strains (HA-MRSA, CA-MRSA) there are strains which do not cross over from skin to blood/organs/etc?"

I would say that to a degree its your body fighting the infection that makes you feel so awful - the immune system kicking into action and depleting your energy reserves and messing things up internally. There may well be strains of MRSA that do not have the necessary virulence factors to allow then to cross over from a wound to the blood but I would imagine it has more to do with other factors such as general health and abililty to keep an infection at bay.

8896
Re: Need Help with MRSA blood tests
Reply #7 by ...
Posted: January 14, 2007 at 07:04
Ive been dealing with MRSA skin lesions for over 2 years. My daughter has caught them. My dad caught it and it was in his blood. My mom has also caught it. I break out in boils ALL THE TIME. Horrible painful boils that make me not want to move. I am in constant pain from that and being sick. I had a blood culture done over a year ago and it was negative but I still break out constantly. My Infectious diesese specialist said to take bleach baths 2 times a aweek for a month then once a week. 1-2 tsp of bleach per gallon of water. Said to disinfect all surfaces and wash everything. Said antibiotics like bactim and doxy will only temporarilty cover up the infection that I have to eradicate it from me skin. I am one of the few that actually has CA MRSA. I am told to constantly disinfect my hands when out places. It's awful.
8916
Re: Need Help with MRSA blood tests
Reply #8 by ladyk
Posted: January 15, 2007 at 17:48
Hi Callie

Thank you for your response. To be honest Iíve felt so gravely ill physically at times during all this I thought if I gave in to ďitĒ and exhaled greatly I would die. It should be known Iíve been through some difficult things in my life and have been known to be a strong woman. I just donít know where the cut off is from feeling gravely ill, and actually being as gravely ill as all the doctors keep telling me I am over and over again, without MRSA (or something / hopefully not the elusive Pseudomonas) showing in my blood. Iíve been told by ID specialists Iím fighting 3 superbugs at the same time. I was happy to learn whatever blood test he did do are returning negative, but I canít get passed being equally skeptical hearing ďnegativeĒ from one doctor and one set of test after all Iíve gone through with MRSA and dozens of doctors. What appears as cycling continues nine months later only on a milder scale, and shorter duration of symptoms. These milder and shorter duration outbreaks could be due to catching lesions in early stage with the use of Bactroban and Phisohex wash prescriptions. Not sure but ďup timesĒ may also be due to taking immune boosting products, possibly responsible for some increase in energy levels.

The infections Iíve experienced are Staphylococcus Aureus and Pseudomonas Aeruginosa first cultured (5 days after surgery) from a deep lateral labial surgical wound which runs the entire ďinsideĒ of my left labia where two doctors cut and explored during a two hour surgery in the ER, followed directly by the first perineum MRSA lesion outbreak. Other chronic infections since all this began are yeast, UTI, bladder, kidney, and finally Clostridium difficile. The symptoms Iíve experienced have been the scariest. Greatest fatigue Iíve ever experienced in my life, malaise, poor appetite to the point of anorexia, weight loss, lack of equilibrium, lack of concentrated thought process and memory, headache, about fainting - walking in a what feels like a tunnel fog like state, nausea, vomiting, night sweats, chronic diarrhea upwards of 8 - 10 times a day for days without end due to C-diff.

The MRSA cross over factor from skin to blood remains a mystery to me.
[Most people will have transient bacteria in the blood and these come from silly things like brushing your teeth (where mouth bacteria enter the blood stream via cuts/bleeding gums) but the body easily deals with this, stops the bacteria multiplying and destroys them.]
I understand your statement above as it seems quite logical when considering less intrusive bacteria forms being killed off by our immune systems. I donít see MRSA in any amount being transient or destroyed naturally once it presents itself whether in blood, soft tissue, or otherwise. I cannot say for sure but it seemed even un-natural methods such as antibiotic therapies didnít seem to have much of an impact on my MRSA since running the course of 12 or so different ones I have consumed over the past nine months. Immune systems even when not compromised doesnít seem to fit either. As ridding the body of MRSA bacteria using our natural defense system doesnít seem to apply when we see Ĺ a football team of healthy individuals who have become afflicted with MRSA.

For example:
1)Lets say one is experiencing MRSA lesion outbreaks. And since MRSA also colonized in the nares, and upon blowing the nose blood is expelled, there has to be an open avenue into the blood stream, yet the blood avenue from the nose bleeding (broken blood vessel) doesnít provide MRSA entry into oneís blood system?

2)Another example, in my situation the swollen tissue was deeply cut into where the only drainage expelled was frank red blood, there was not purulent discharge, there was a definite open avenue into my blood stream due to this surgical wound and yet MRSA if one relies on the recent blood tests has not crossed over infecting my blood?

These are my big questions. And why it seems to me a MRSA strain issue.

Thanks for letting me pick your brain Callie

8927
Re: Need Help with MRSA blood tests
Reply #9 by ladyk
Posted: January 15, 2007 at 18:04
Lauren

Hi. Thank you, yes I understand and have/continue to do all you have advised. I even wash all vegetables and fruits with soap and water prior to eating. I bleach my entire house and know I must be doing a good job in that department as my husband and adult daughter I live with have not contracted MRSA.

8928
Re: Need Help with MRSA blood tests
Reply #10 by Callie
Posted: January 15, 2007 at 18:12
Hi again ladyk.

Both examples you give would more than likely increase the risk of someone developing MRSA septicaemia but they don't definately mean it will happen if that makes sense.

I would like to add some to your nasal colonisation example in that about 30% of the population carry S. aureus in the nose and Im sure of that 30% most of them sneeze and break blood vessels but the amount of people that develop septicaemia from this must be incredibly low - I have no idea on the stats but Im sure if it was common we would know about it.

I would say that that scenario would give the MRSA and whatever other beasties are up the persons nose the opportunity to get in to the blood but for whatever reason it doesnt happen often or it does but the beasties dont survive.

The second example ...well Im not so sure about! most of what Im saying is just guess work Im afraid so don't put too much into what Im saying!

Blood cultures will only pick up any bacteria present in the blood then and there when the sample is taken - perhaps the MRSA did cross over but it was only transient and the blood culture missed it?

I think Im going to have to do a bit more digging to find out about MRSA strains and their relative virulence but its certainly a possibilty that you have a strain which is less able to get into the blood stream and survive.
8929
Re: Need Help with MRSA blood tests
Reply #11 by ladyk
Posted: January 15, 2007 at 19:46
Callie

Perhaps Sandi who wrote...

[Reply #1 by sandi Posted: January 8, 2007 at 05:08 I have never had a blood test that showed MRSA. I have had fluid from around my ankle tested to show MRSA. I had one Boil tested to show MRSA.]

...and myself having had positive cultured MRSA lesions, are dealing with HA-MRSA where virulence is proving less pathogenic than septicemia prone strains which seems more prevalent in crossing over when CA-MRSA is present? Just a thought. Guess that is where all the PVL debate came from. Iíd say Staphylococcus has proven it would attempt to capitalize on the ďentryĒ of any host body. Mutating. Learning to enter, and entering. MRSA. MRSA strains each more virulent than itís predecessor. Seems the nature of such a tiny beast, a formidable opponent as they say, to be sure.

Thanks for the great conversation, these are things I think about often, this time I got caught think typing out loud.

Have you contracted MRSA?
8931
Re: Need Help with MRSA blood tests
Reply #12 by Feeling alone
Posted: January 22, 2007 at 01:47
LadyK I replied to your answers for me but I think I replied to myself. If you would not mind to look back under the one you answered too. Thanks so much for your time...
8989
Re: Need Help with MRSA blood tests
Reply #13 by ladyk
Posted: January 25, 2007 at 03:34
Replied under your post. Your welcome.
9026
Re: Need Help with MRSA blood tests
Reply #14 by Linda
Posted: December 7, 2018 at 01:34
what is the marker to look for after you've had bloodwork done? is there a acronym I'm suppose to
look for in the list of things from the bloodwork results

25600
   1
Reply to this topic    or     Start New Topic

Your Name:
Reply Subject: Re: Need Help with MRSA blood tests
Comments:
(You may enter up to 3001 characters)

characters left
Type the characters shown in the image for verification:
Change Image
Write the characters in the image above